In the News — Acute Behavioural Improvement
following plant polysaccharide intake
Study shows a single serving of Ambrotose® complex enhances memory
February 12, 2014
In a double-blind, placebo-controlled human clinical trial published in Nutritional Neuroscience, healthy middle-aged adults who consumed Ambrotose complex powder showed significant improvements in tests measuring recognition and memory compared with subjects taking a placebo or sucrose.*(1) According to
the study authors, this is the "first report of acute behavioural improvement following plant polysaccharide intake in healthy middle-aged adults under conditions of mental fatigue. The findings suggest that certain NSP** may enhance memory performance through mechanisms other than elevated blood glucose." Previous studies have reported similar benefits following 12 weeks of intake of Ambrotose complex (2),(3).
The study was conducted by Dr. Talitha Best, a post-doctoral research fellow at the Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia (UniSA), Dr. Peter Howe of the Clinical Nutrition Research Centre, University of Newcastle, Newcastle, Australia, Dr. Janet Bryan, School of Psychology, Social Work and Policy, University of South Australia, Adelaide, Australia, Dr. Jonathan Buckley of the Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia and Andrew Scholey of the Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, Australia.***
Link to publication: http://www.maneyonline.com/doi/abs/10.1179/1476830513Y.0000000101
* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
** NSP= non-starch polysaccharides
***Mannatech provided partial funding and provided the Ambrotose supplement and placebo used in this study.
Mannatech's CEO and CSO Featured in Article about Open Innovation
April 19, 2013
Mannatech's CEO and Chief Science Officer Dr. Robert Sinnott was recently interviewed by Nutraceuticals World magazine for their ongoing series "Open Innovation in Nutraceuticals & Functional Foods." In the article, industry thought leaders were invited to discuss Open Innovation (OI) and share their experiences and challenges using it to leverage the development of new products. Dr. Sinnott shared Mannatech's successful approach to employing (OI), using the MannaThinksm online forum, commenting: "The proof of the success of our innovative application of OI is, of course, reflected in the bottom line. We believe that our Associates can sell these products with passion because they were created with their input and are thus fundamentally aligned with their beliefs and their needs." Mannatech's unique application of OI has contributed to the development of numerous successful products, including PhytoBurst® chews, Omega-3 with Vitamin D3 capsules, GI-ProBalance® slimsticks, BounceBack® capsules and Mannatech's newest flagship product, NutriVerus™ powder
Nutraceuticals World is a trade publication that serves the manufacturers of dietary supplements, functional foods and nutritional beverages. The entire interview can be read here.
Dr. Rob Sinnott
* This statement has not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.
Exploring Cognitive Benefits of Mannatech Glyconutrients and other Polysaccharides
Review of the Effects of Polysaccharides on Brain Function
Mechanisms that might explain the cognitive benefits of Mannatech glyconutrients
and other polysaccharides are explored.
(COPPELL, Texas) March 27, 2012---Mannatech,Incorporated (NASDAQ:MTEX), the leading innovator and provider of nutritional supplements and skin care products based on Real Food Technology® solutions, recently announced the publication of a comprehensive literature review reporting the effects of polysaccharides on brain function.
Dr. Erika Nelson, a neuroscientist, and her colleagues reviewed controlled studies assessing various roles of exogenous saccharide compounds and polysaccharide-rich extracts on brain function, with a significant focus on benefits derived from oral intake. Her review includes a discussion of five randomized, double-blind, placebo-controlled clinical trials that indicate that Ambrotose® complex, a Mannatech product, positively impacts well-being, memory, cognitive function and mood in healthy adults.*
Numerous preclinical studies were also identified that indicate various polysaccharides can modify behavior, enhance synaptic plasticity and provide neuroprotective effects.
"Mannatech has consistently demonstrated a strong commitment to evaluating the impact of oral polysaccharide compounds on human health", said Dr. Robert Sinnott, CEO and Chief Science Officer at Mannatech.
"In 2010, we published a review--which has been of great interest to the scientific community; which consolidated the extant literature reporting significant impacts of oral polysaccharides on immune function. Today, we are once again pleased to offer an important consolidation of the literature investigating the impact of oral polysaccharides on brain health and function. This literature review both clarifies the current state of the science in this area and suggests appropriate avenues for future research that will help us better understand the benefits of these important compounds."
Dr. Nelson earned her BS in Genetics from the University of Kansas in Lawrence and went on to obtain her PhD in Neuroscience at the University of Texas Southwestern Medical Center in Dallas.
She has published a number of papers on neurodevelopmental disorders and brain epigenetics. A candidate for a Masters of Business Administration at the University of Texas at Dallas, Dr. Nelson is also a consultant for Mannatech.
Co-authors of the review include Dr. Robert Sinnott; Dr. Talitha Best, a scientist with dual appointments at the University of South Australia, Adelaide, and Swinburne University of Technology, Victoria, Australia; and Jane Ramberg, Director of Product Substantiation at Mannatech.
